Sure, just reboot and do a backup in Safestrap while on the safe side. It will back up your data and system. You can then flash another ROM, following the directions for that particular ROM, and back it up as well. Do that as many times as you like or until you run out of space. Obviously, any ROM you pick must be compatible with your non-safe kernel.
The backups are stored in /safestrap/backup on either internal or external storage (you choose that when you make the backup). Once you've played all you want and are ready to go back to what you have now, just wipe /cache & dalvik cache and restore the backup.